AI-Generated Image Detection

Detection of AI-generated images across microscopy, histology, cell plates, animal imaging, medical scans, and Western blots & gels—before they compromise your research.

Why AI-Generated Images Matter

AI-generated models have evolved significantly in the past few years and can now mimic scientific images with high fidelity – even microscopy textures and blot banding. Proofig AI detects AI-generated images early to help prevent desk rejections and retractions, and protect the credibility of your work. Like an immune system adapting to new pathogens, we continue to evolve as new threats emerge.

Data Misinterpretation

Synthetic images can alter how findings are perceived and evaluated.

Rejection or Retraction

May lead to editorial rejection before publication—or a formal retraction afterward.

Reputational Damage

Harms the credibility of authors, institutions, and journals alike.

Loss of Trust in Science

Erodes reader confidence and affects downstream research.

AI-Generated Image Categories We Detect

 Proofig AI uses multi-modal models that are continuously updated to detect six key scientific image types, with ongoing expansion to cover new manipulation methods and emerging threats.Multi-modal models, continuously updated across six image types, and working to increase coverage as new threats emerge.

AI-generated microscopy image used to demonstrate how AI-generated image detection identifies synthetic cellular patterns.

Microscopy

AI-generated histology image showing fabricated tissue structures used to illustrate AI-generated image detection.

Histology

AI-generated fluorescent cell plate image demonstrating how AI-generated image detection flags synthetic colony imagery.

Cell Plates

AI-generated animal imaging scan with artificial heat-map coloration used as an example for AI-generated image detection.

Animal Imaging

AI-generated medical scan image illustrating synthetic radiological features examined in AI-generated image detection.

Medical Scans

AI-generated western blot and gel pattern showing fabricated band structures used to demonstrate AI-generated image detection.

Western Blots & Gels

Think you can spot the AI fakes?

Test yourself with our quick quiz and see how well you can tell authentic images from AI-generated ones.

How It Works

Upload Your Manuscript Drag and drop your PDF or DOCX file—no formatting changes needed.

Step 1
Step 2

AI-Powered Analysis The system scans all images for potential issues—including AI-generated content.

Review and Validate Check flagged items, investigate further with forensic tools (e.g., color maps, Emboss, histogram equalization), and decide what to include.

Step 3
Step 4

Download a Final ReportGet a detailed PDF report you can use to uphold research integrity within your lab or team.

Industry-Leading AI Detection Accuracy

AI-Generated Images Detection Benchmarks
Microscopy

True Positives: 95.41%
False Positives: 0.0093%

Dataset: 200K real images

Western Blot

True Positives: 97.68%
False Positives: 0.0020%

Dataset: 250K real images

Trusted by Leading Institutions and Publishers

250K+ Manuscripts

Scanned using Proofig AI to uphold research integrity

Global
Trust

Adopted by top-tier publishers, journals, and research institutions

Seamless Integration

Integrated into pre-submission and editorial screening workflows

Integrity Support

Used by researchers, editors, and ethics officers worldwide

Proofig helped us catch issues we would’ve missed entirely.

Editorial Team
High-Impact Journal

Ready to Safeguard Your Figures?

Further Resources