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Proofig News

April 2023

Proofig features in Microscopy and Analysis

A captivating set of four microscopy images unveiling a fascinating phenomenon of partial overlap with a 90-degree rotation. Each image showcases distinct microscopic specimens with intricate structures, exhibiting a remarkable alignment where only a portion of the structures overlaps, with a rotation of 90 degrees. This discovery in microscopy research raises intriguing questions about the underlying mechanisms and potential implications of such rotational alignments. These visual findings highlight the complexities of microscopic imaging and the intricate nature of capturing detailed structures. Understanding the factors contributing to partial overlap and 90-degree rotation can deepen our understanding of microscopic phenomena and enhance our knowledge of imaging techniques in microscopy.

Images are an integral part of communicating valuable results in scientific papers, so researchers and publishers must take care to ensure they only include clear and accurate images. 


This article, featured in Microscopy and Analysis, outlines the importance of image integrity, how issues can occur and how to proactively improve how we review images.


Read the full piece in the April edition and online

August 2022

Taylor & Francis trials Proofig to help detect image duplication

logo Taylor & Francis

Leading publisher Taylor & Francis Group is now using Proofig AI image integrity software as part of an ongoing pilot programme to prevent image integrity issues in academic journals.


Taylor & Francis has a reputation of sharing high-quality, cross-disciplinary knowledge and speciality research that shapes human understanding and drives change.


We encourage other publishing houses that really care about integrity to contact us as well. Read the full announcement on the Taylor & Francis site.

August 2022

Integrity investigation into multi publications related to Alzheimer's disease,  showcases the importance of efficient image analysis before publication

An image showcasing a side-by-side comparison of four Western blot gel samples. The image highlights distinct gel lanes, each representing different experimental conditions or samples. These Western blot gels provide valuable visual information about the protein expression patterns and allow for comparisons and analysis between the different samples. This image serves as a useful reference for researchers and scientists studying protein analysis and related techniques in Western blot experiments.

Recently, a considerable crisis emerged in the Scientific community, potentially affecting the pharmaceutical industry significantly. This crisis relates to suspected integrity issues that undermine the core of primary findings linking Alzheimer's disease, a neurodegenerative disease that causes 60–70% of cases of dementia.

In 2006 Nature published the study, A specific amyloid-β protein assembly in the brain impairs memory. Now, an investigation by Science magazine suggests that the paper included image integrity issues.

Whether innocent mistakes or misconduct, current issues in published research can be easily avoided using AI such as Proofig.

Read the original paper and find out more about the investigation here.

August 2022

The Journal of Clinical Investigation 
screens papers with Proofig

In July 2021, the Journal of Clinical Investigation began using Proofig software to improve image integrity in its journals. Since implementing the software as part of its review process, editors have more easily detected duplications and manipulations before publication. 

Thank you to the editors for sharing your experience with Proofig!

Read more on the Journal of Clinical Investigation website and its article, Data we can trust.

Proofig Icon

July 2022

Proofig appears in Biotechnology News

An intriguing image presenting a comparison of six microscopy samples, revealing multiple integrity issues within the dataset. The samples exhibit various anomalies, including rotation, flipping, partial overlap, and other irregularities. These discrepancies raise concerns regarding the accuracy and reliability of the captured data. The presence of such integrity issues highlights the importance of meticulous quality control in microscopy research, ensuring the validity and trustworthiness of experimental results. Detecting and addressing these issues is vital for maintaining the integrity and credibility of scientific investigations. This visual evidence serves as a reminder of the challenges involved in ensuring accurate representation of microscopic findings and the ongoing efforts to uphold rigorous standards in scientific research.

Biotechnology News recently featured Proofig, explaining how researchers can use the software to proactively check image integrity, increasing their chances of publication and protecting their reputation.

Read the full article here.

May 2022

Proofig appears in Scientist Live

An image showcasing a side-by-side comparison of four Western blot gel samples. The image highlights distinct gel lanes, each representing different experimental conditions or samples. These Western blot gels provide valuable visual information about the protein expression patterns and allow for comparisons and analysis between the different samples. This image serves as a useful reference for researchers and scientists studying protein analysis and related techniques in Western blot experiments.

How damaging can one image be? In scientific paper publication, a single image is worth your entire reputation.

Scientist Live recently featured an article about the consequences of image integrity issues and how to prevent them, including by using Proofig. Read the full article on the Scientist Live website.

May 2022

Mary Ann Liebert Inc. embraces Proofig technology

Micro-Biology image

Mary Ann Liebert, Inc. is a leading independent publisher of scientific, technical, and medical content that publishes over 100 peer-reviewed journals, leading trade magazines, and specialized newsletters, in addition to society membership management and conferences.

To improve quality assurance, the Liebert publishing team will use the Proofig software as part of its submissions-through-decision suite of integrity checks, as well as to assist in investigating any issues found post-publication.

Proofig featured in Health Tech Digital

May 2022

microscopy image

Scientific trade magazine Health Tech Digital has featured Proofig technology. The article shares how researchers and publishers can use the software to proactively check papers for image integrity issues before publication. Read the full article here

April 2022

Proofig appears in Drug Discovery Today — Launching the first commercial automated image duplication and manipulation detection software for scientific publications

manuscript editor image

To provide publishers, universities and scientific researchers with a tool to check image integrity before submission, Dr. Dror Kolodkin-Gal, founder of Proofig, have launched an automated image integrity detection software. This automated artificial intelligence (AI) tool detects the majority of forms of image duplication and some of the manipulation. Publishers and researchers can use the tool to accurately check images before submission, reducing the risk of post publication retraction.

Proofig’s software extracts images from papers and compares each image to itself to find duplications in images and all images to one another to find duplications between images. It will also compare each flipped image with the other images in the uploaded files to look for cases of flipped images, checking a typical paper in minutes.


Publishers such as the American Association for Cancer Research (AACR) and the American Society for Clinical Investigation (ASCI) have already integrated Proofig’s software into their review processes. Universities are also benefitting from the technology. 

Read more here:

Dec 2021

Nature: Journals adopt AI to spot duplicated images in manuscripts

An intriguing image showcasing a comparison of two microscopy samples with notable alterations of scale and 180-degree rotation. The samples demonstrate intentional modifications, where one sample has been scaled to a different size, while the other has undergone a complete reversal in orientation through a 180-degree rotation. These deliberate manipulations raise questions about the motivations behind such modifications and their potential implications for data interpretation. This visual evidence underscores the importance of accurate representation and integrity in microscopy research. Understanding the effects of scale adjustments and rotational transformations can contribute to improving imaging techniques and enhancing the reliability of microscopic analysis.

Oct 2021

SAGE Publishing Integrate Proofig's Solution

lego stack image

To ensure its published scientific manuscripts include reliable and undistorted images, global academic publisher SAGE Publishing, is now using software from image-proofing technology expert, Proofiger Ltd. SAGE publishing will use Proofig software for pre-publishing analytics on five of its life science journals to provide quick detection of any sub-image duplications or manipulations prior to publication.

“Proofig offers our editorial team the peace of mind that problematic images will be found in manuscripts before they are published,” explained Helen King, Head of Transformation at SAGE Publishing. “In the future, checking for image errors and plagiarism will become a standard part of publisher workflows, so by implementing Proofig software SAGE will be ahead of the curve.” 

We are more than honored to be chosen by an outstanding publisher such as SAGE to take part in the important change led by the life science publishing community, affirming the responsibility we all take to prevent image integrity issues in research papers. 

Jul 2021

ASCI Integrate Proofig's Solution

Eye analyzing photo to describe the new collaboration between ASCI and Proofig

The American Society for Clinical Investigation has chosen to integrate Proofig in order to ensure image integrity in their future publications in their journals JCI & JCI Insight.


We look forward to our new collaboration as we are honored to be chosen as a screening software by one of the leading medical journals publishers.

Our Proofig team is set on a mission to improve publication integrity, and we are always grateful when given the chance to do so

Feb 2021

AACR Integration with Proofig solution for image manipulation & duplication detection
  • At Proofig, we're pleased to announce that AACR, the first and largest organization in the world dedicated to advances in all areas of high-quality, innovative cancer research, has integrated the Proofig solution to detect image duplication and modification prior to publication.

  • The Proofig SaaS Solution harnesses the power of computer vision, image processing, and artificial intelligence to ensure image integrity in scientific publications and to protect the reputation of scientists and the scientific community.

  • We are delighted to serve such a prominent organization, contributing to strengthening the integrity and QA of the scientific publication process.

Nov 2020

Proofig launched automatic SaaS service for publishers

Proofig software detected Image plagiarism (duplication) via peer review process of academic journal editors
  • Proofig has launched a new SaaS platform to serve editors, research institutions, and researchers, who can upload their articles and receive a full analysis report within minutes.

  • Publication review processes for image integrity (duplication, manipulation & paper mill) have never been so easy, fast and effective. Proofig enables publishers to utilize its functionalities at scale as part of automatic review processes using APIs.

May 2020

Proofig features in Nature

microscope image
  • Proofig in Nature: At Proofig, we're delighted that the world's top scientific publishers are discussing the pressing need to address the problem of image duplication and manipulation and we're very proud to be named among the pioneers of image-proofing technology to ensure scientific publications’ integrity by Nature

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