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1 in 4 Articles Has Image Integrity Issues – Is Yours at Risk?

Ensuring the integrity of your scientific images is crucial. At Proofig, we've found that 1 in 4 scientific articles has image integrity issues

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These issues can lead to retractions and damaged reputations

Our Solutions

Proofig AI utilizes a vast database exclusively for detecting plagiarism, while also identifying duplications and manipulations within individual manuscripts.

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PubMed Source Plagiarism

Detection of Reuse of Sub-Images From Published Manuscripts (Plagiarism). Utilizing PubMed's Source database, which contains tens of millions of images.

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Duplication & Reuse

Detection of Duplication or Reuse Within a Single Manuscript, Including Scaling, Rotation, Flipping, Full and Partial Overlap, and Additional Irregularities.

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Alteration & Manipulation

Detection of Alteration or Manipulation Within a Single Sub-Image, Including Cloning, Editing, Deletion, and Splicing.

Why Choose Proofig AI?

Discover Proofig's Partner: Elsevier Collaboration for Enhanced Research
Springer Nature Collaboration: Strengthening Research Efforts with Proofig Partnership
This image features the logo of Science (, a leading scientific journal.
Proofig Partner Highlight: AACR's Contribution to Cutting-Edge Cancer Studies
Discover Proofig's Collaboration with the Royal Society for Chemistry: Advancing Scientific Analysis and Research
Exploring the Proofig-ASCI Publication Partnership: Advancing Research and Knowledge through Collaborative Synergy

Proofig is the leading image integrity solution, trusted by top-tier journals and institutions worldwide

Discover Proofig's Collaboration with Acme Biologists: Elevating Image Quality and Plagiarism Detection in Biology Research
Unveiling the Proofig-Mary Ann Liebert, Inc Collaboration: Advancing Image Analysis in Scientific Publishing
Compuscript Partners with Proofig for Image Quality Services and Plagiarism Detectio
Exploring the Proofig-SAGE Publication Partnership: Advancing Research and Knowledge through Collaborative Synergy
Proofig and FSG Join Forces: Enhancing Image Quality Services and Plagiarism Detection
Exploring the Proofig-Taylor & Francis Partnership: Advancing Scientific Image Analysis and Research Integrity

Image Integrity Challenges

Explore the common risks associated with image manipulation in scientific research.

Four microscopy images compared; one flipped, indicating data manipulation.
Comparison of four microscopy images; one shows signs of cropping and rotation
This image shows four western blot bands, with two of them displayed at an angle, indicating rotation
This image displays four western blot bands, two of which are flipped, altering their original orientation.
Image depicting a Spliced Western Blot, enhanced with a histogram equalization filter to emphasize its features.
Image showcasing a Spliced Western Blot, highlighted using a histogram equalization filter for clearer visualization
Flow Cytometry Plots (FACS

Join the Proofig Community

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Discover More About Proofig

To learn more about Proofig, read testimonials, and understand the full scope of our capabilities, click the button below to explore our website.

Photo of Jana Christopher

“Image integrity issues in the scientific literature are more prevalent than many readers would expect, and notably so in the life sciences. In recent years, an increasing number of scientific journals have adopted pre-publication image screening. Expertise in this area has developed, whilst the need for reliable and user-friendly automated tools to screen large volumes of image data at scale has grown accordingly.  

I have found Proofig to be impressively strong in detecting duplications and part-duplications in Western blots and microscopy images. It works fairly quickly and reliably across several figures, whilst being robust to rotation, flipping, resizing, and colour changes. The makers recently also added Flow Cytometry plots to their catalogue of screen-able image types.


The system automatically generates a report summarizing individual, selectable findings in a clear manner, and users can also re-visit previously screened items in their own database. Whilst it remains essential for an experienced user to verify and interpret individual findings, I believe Proofig is a very valuable tool for duplication detection, and suited to effectively assist journals’ image integrity screening routines”.

Jana Christopher

Image Data Integrity Analyst


Hear what renowned editors and scientists are saying about Proofig:

Proofig achievements


Average manuscripts with findings


Scanned Manuscripts


Scanned pages


Processed Subimages


Image detection precision


Text detection precision


Western band alteration

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